Tachjian A, et al. Natural Medicines. It is usually caused by narrowing of your coronary arteries due to a build-up of a fatty substance called atheroma. 2010; doi:10.1016/j.jacc.2009.07.074. Accessed Sept. 7, 2022. Tell your doctor if this medication stops working well (for example, you have more frequent or worsening chest pain). Review/update the Manufacturer's PIL, Imdur 60 mg tablets; TopRidge Pharma Ltd, The electronic Medicines Compendium. No, that's not true all the time. Profen and Metoclopramide drug interaction, Metoclopramide and Nitrostat drug interaction, Metoclopramide and Alfentanil drug interaction, Risperdal and Metoclopramide drug interaction. It works to relax your blood vessels. To use the sharing features on this page, please enable JavaScript. If you do not remember until your next dose is nearly due, then leave out the forgotten dose and take your next dose when it is due. Isosorbide mononitrate (Monoket) can cause headaches, dizziness, or lightheadedness. Isosorbide mononitrate. Learn to reduce stress through mindful living. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you. All rights reserved. The extended-release tablet usually is taken once daily in the morning. I would rather take the chance of a heart attack than have no quality of life. Do not share this medication with others. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. privacy practices. It works and leaves the body quickly, so it needs to be taken twice a day. 41% of reviewers reported a positive effect, while 50% reported a negative effect. . Drug interactions may change how your medications work or increase your risk for serious side effects. Do not drive, use machinery, or do anything that needs alertness until you can do it safely. amlodipine, lisinopril, aspirin, metoprolol, furosemide, carvedilol, propranolol, spironolactone, atenolol, diltiazem. Yet significantly fewer patients had headache on low dosage than on high dosage (45 vs 57, P < 0.02). This risk may be even higher for certain groups. isosorbide mononitrate prices. Clipboard, Search History, and several other advanced features are temporarily unavailable. Isosorbide mononitrate belongs to the group of medicines called nitrates. and transmitted securely. The https:// ensures that you are connecting to the Isosorbide-2,5-dinitrate and isosorbide-5-mononitrate, the low-potent organic nitrates, are directly metabolized in the endoplasmic reticulum of the vascular smooth muscle cells via cytochrome P450 enzymes, resulting in direct production of nitric oxide (Mnzel et al., 2005).In contrast, the highly potent organic nitrates such as glyceryl trinitrate (GTN) and pentaerythritile tetranitrate . Contraindications: Isosorbide mononitrate should not be used in cases of acute myocardial infarction with low filling pressure, acute circulatory failure (shock, vascular collapse), or hypertrophic obstructive cardiomyopathy (HOCM), constrictive pericarditis, low cardiac filling pressures, aortic/mitral valve stenosis and diseases associated with a raised intra-cranial pressure e.g following a head trauma and including cerebral haemorrhage. View World Anti-Doping Agency classifications, Prevention of Thromboembolism in Atrial Fibrillation, Prosthetic Heart Valves - Thrombosis Prophylaxis, Prosthetic Heart Valves - Mechanical Valves - Thrombosis Prophylaxis, Revascularization Procedures - Prophylaxis. Danshen. Hawthorn. This medication belongs to a class of drugs known as. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Disclaimer. https://naturalmedicines.therapeuticresearch.com. Do not stop taking it without consulting your doctor. Accessed Sept. 7, 2022. Talk to your pharmacist for more details. A total of 195 drugs are known to interact with isosorbide mononitrate: A total of 330 drugs are known to interact with aspirin: A total of 239 drugs are known to interact with nitroglycerin: No known alcohol/food interactions. The information contained in the Truven Health Micromedex products as delivered by GoodRx is intended as an educational aid only. Call your doctor for medical advice about side effects. official website and that any information you provide is encrypted May also be prescribed off label for Esophageal Spasm. This site complies with the HONcode standard for trustworthy health information: verify here. National Library of Medicine Some side effects may occur that usually do not need medical attention. This chest pain can feel more intense or painful than it was before you began taking isosorbide mononitrate (Monoket). Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken. If you miss a dose, take it as soon as you remember. Registered in England and Wales. Evening primrose. AskMayoExpert. Your body can get used to isosorbide mononitrate (Monoket), and the same amount of medication might no longer work as well as it used to. Never give it to other people even if their condition appears to be the same as yours. What should I know about storage and disposal of this medication? Avoid combinations; the risk of the interaction outweighs the benefit. Garlic. https://naturalmedicines.therapeuticresearch.com. It is components of vit. Prescription and OTC Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Danshen can interact strongly with some heart medicines, such as: Evening primrose may raise your risk of bleeding if you also take a blood thinner, such as: Garlic may raise your risk of bleeding if you also take a blood thinner, such as: Ginkgo biloba may raise your risk of bleeding if you also take a blood thinner, such as: If you take ginseng with warfarin, it may lessen how well warfarin works. This is not a complete list of possible side effects. Along with its needed effects, a medicine may cause some unwanted effects. As precautionary measure, breast-feeding should be discontinued during treatment with isosorbide mononitrate. Change positions slowly until your body is used to the medication. Some products that may interact with this drug include: drugs to treat erectile dysfunction-ED or pulmonary hypertension (such as sildenafil, tadalafil), riociguat. Advertising revenue supports our not-for-profit mission. Background: Patient does not provide medical advice, diagnosis or treatment. "Mayo," "Mayo Clinic," "MayoClinic.org," "Mayo Clinic Healthy Living," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Fish Oil (omega-3 polyunsaturated fatty acids), Email this report to a friend, doctor, or patient, isosorbide mononitrate consumer information. If you have been told by a doctor you have low levels of iron in your blood (anaemia), or low levels of oxygen in your blood (hypoxaemia). Dated August 2017. This branded product is no longer on the market. Dated October 2016. Is isosorbide mononitrate (Monoket) the same as nitroglycerin (Nitrostat)? Information is also available online at https://www.poisonhelp.org/help. For instance, many herbal supplements that are used often interact with the blood thinner warfarin (Jantoven). The information on this page is written and peer reviewed by qualified clinicians. Read our editorial policy. Call your doctor if you have any unusual problems while you are taking this medication. Tell your pharmacist what products you are using, and ask how to use them safely (especially cough-and-cold products, diet aids, or NSAIDs such as ibuprofen/naproxen). In: Current Medical Diagnosis & Treatment 2022. Swallow the extended-release tablets or capsules whole; do not crush, chew, or divide them. Keep all medicines out of the reach and sight of children. All rights reserved. HHS Vulnerability Disclosure, Help Your doctor will prescribe you a short-acting nitrate for you to take if this happens. May also be prescribed off label for Esophageal Spasm. A very serious allergic reaction to this drug is rare. Properly discard this product when it is expired or no longer needed. Isosorbide mononitrate dilates (widens) blood vessels, making it easier for blood to flow through them and easier for the heart to pump.Isosorbide mononitrate is used to prevent angina attacks (chest pain). Some products have ingredients that could worsen your heart failure. Available for Android and iOS devices. Also, it is not intended to be taken just before physical activities (such as exercise or sexual intercourse) to prevent chest pain. Higher than recommend dosage of sublingual isosorbide dinitrate for treating angina pectoris: a case report and review of the literature. You may report side effects to Health Canada at 1-866-234-2345. Sign up for free, and stay up to date on research advancements, health tips and current health topics, like COVID-19, plus expertise on managing health. The Swedish Multicentre Group. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. See also: nitroglycerin side effects in more detail. 2021 May 11;39:28. doi: 10.11604/pamj.2021.39.28.22180. The table below contains some of the most common ones associated with isosorbide mononitrate. Alcohol can make the side effects from isosorbide worse. The drug donates nitric oxide to the body, which is similar to all other Isosorbide mononitrates. information and will only use or disclose that information as set forth in our notice of 45, Migranal), ergoloid mesylates (Hydergine), ergotamine (in Cafergot, in Migergot), methylergonovine (Methergine), methysergide (Sansert; no longer available in the U.S.), and pergolide (Permax; no longer available in the U.S.); medications for high blood pressure, heart failure, or an irregular heartbeat. Take the container with you, even if it is empty. While both isosorbide mononitrate (Monoket) and nitroglycerin (Nitrostat) are both nitrate vasodilators, they are not the same medication. It has a very short duration of action and may not be suitable for some people. Be sure to mention any of the following: aspirin; beta blockers such as atenolol (Tenormin, Tenoretic), carteolol , labetalol (Trandate), metoprolol (Lopressor, Toprol-XL, in Dutoprol, in Lopressor HCT), nadolol (Corgard, in Corzide), propranolol (Hemangeol, Inderal, Innopran), sotalol (Betapace, Sorine, Sotylize), and timolol; calcium channel blockers such as amlodipine (Norvasc, in Amturnide, in Tekamlo), diltiazem (Cardizem, Cartia, Dilt-CD, others), felodipine (Plendil), isradipine, nifedipine (Adalat CC, Afeditab, Procardia), and verapamil (Calan, Covera, Verelan); ergot-type medications such as bromocriptine (Cycloset, Parlodel), cabergoline, dihydroergotamine (D.H.E. Prescription only Prescribed for Angina, Heart Failure, Angina Pectoris Prophylaxis. Talk to your doctor or pharmacist about lifestyle changes that might benefit you. Using this medicine with any of the following medicines is not recommended. This document does not contain all possible drug interactions. Please upgrade your browser or download modern browsers from here! Can isosorbide mononitrate cause problems? Receive price alerts, news, and other messages from GoodRx about isosorbide mononitrate (Monoket) and other healthcare topics and relevant savings offers. Both versions of isosorbide mononitrate (Monoket) contain the same active ingredient. Click here for an email preview. Isosorbide mononitrate vs. Amlodipine besylate, Isosorbide mononitrate vs. Bisoprolol fumarate, Isosorbide mononitrate vs. Diltiazem hydrochloride, Isosorbide mononitrate vs. Isosorbide dinitrate, Isosorbide mononitrate vs. Metoprolol succinate, Isosorbide mononitrate vs. Metoprolol tartrate, Isosorbide mononitrate vs. Nitrolingual pumpspray, Isosorbide mononitrate and Aspirin (7,880 reports), Isosorbide mononitrate and Furosemide (6,020 reports), Isosorbide mononitrate and Amlodipine (3,554 reports), Isosorbide mononitrate and Simvastatin (3,508 reports), Isosorbide mononitrate and Omeprazole (3,422 reports), Isosorbide mononitrate and Lisinopril (3,099 reports), Isosorbide mononitrate and Metformin (2,822 reports), Isosorbide mononitrate and Carvedilol (2,589 reports), Isosorbide mononitrate and Clopidogrel (2,524 reports), Isosorbide mononitrate and Acetylsalicylic acid (2,355 reports). Prescription and OTC Aspirin relieves pain and inflammation and helps to thin the blood. Changing positions slowly can help lessen dizziness. Alternative drugs to the conditions Isosorbide mononitrate treats: Angina High blood pressure Stable angina Chest pain Heart disease Heart attack Angina unstable Heart disease congenital Coronary heart disease Heart failure Pulse Heart rate irregular Coronary artery spasm Angioplasty Let your doctor know immediately if you continue to experience these symptoms or if they worsen over time. In the US - Call your doctor for medical advice about side effects. 2023 Lybrate, Inc. All rights reserved. Pricing based on most commonly-filled versions: 180 tablets of isosorbide mononitrate 10mg. Talk to your doctor if you are using marijuana (cannabis). tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. To avoid this, if you are taking more than one dose a day, your doses may not be prescribed at equal intervals throughout the day. Although not all of these side effects may occur, if they do occur they may need medical attention. This side-effect usually disappears after a few days, Do not drive and do not use tools or machines while affected, If either of these becomes troublesome, speak with your doctor. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Use this medication regularly to get the most benefit from it. Contact your doctor immediately if you experience any of the following: The following side effects may get better over time as your body gets used to the medication. To avoid this problem, get up slowly, resting your feet on the floor for a few minutes before standing up. There are 195 drugs known to interact with It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. Lifestyle changes such as dietary changes, exercise, and not smoking may help this drug work better. When used regularly on a long-term basis, this helps prevent angina attacks from occurring. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. It took me a few weeks to adapt to it, but the effect on preventing chest pain was dramatic. No you may not. Isosorbide mononitrate helps to prevent angina chest pain from developing. Results: Browse all drugs on eHealthMe. What is the difference between the immediate-release (IR) and extended-release (ER) versions of isosorbide mononitrate (Monoket)? Using this medicine with any of the following medicines is not recommended. There are 7 disease interactions with isosorbide mononitrate which include: Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Nitrates, although important for the management of angina pectoris, cause significant headache in many patients. Which drugs or supplements interact with isosorbide mononitrate? Can cause dizziness, especially when you change positions, Interacts with erectile dysfunction medications. McGraw Hill; 2022. https://accessmedicine.mhmedical.com/search. Are you looking for information on isosorbide dinitrate (Isordil) instead? Do not use medications containing isosorbide dinitrate while using isosorbide mononitrate. For these reasons, before you start taking isosorbide mononitrate it is important that your doctor knows: Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. Take care, thanks. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. Your doctor will tell you which is the right dose for you, and this will also be printed on the label of the pack to remind you about what the doctor said to you. Tell your doctor right away if you have any serious side effects, including: fainting, fast/irregular/pounding heartbeat. Medicines Complete BNF 84th Edition; British Medical Association and Royal Pharmaceutical Society of Great Britain, London. https://naturalmedicines.therapeuticresearch.com. If you have any problems with the way your liver works, or any problems with the way your kidneys work. Healthcare data is obtained from a number of sources including the Food and Drug Administration (FDA). Headaches can be a sign that the medicine is working, and they might lessen with continued use of the medication. Do not start, stop, or change the dosage of any medicines without your doctor's approval. Treatment and prognosis of heart failure with preserved ejection . Prescription and OTC Aspirin relieves pain and inflammation and helps to thin the blood. Isosorbide comes as a tablet, an extended-release (long-acting) tablet, and an extended-release capsule to take by mouth. You can consult me online for homeopathic treatment. Isosorbide is in a class of medications called vasodilators. Isosorbide mononitrate is also sometimes prescribed alongside other medicines for people with heart failure. Imdur (isosorbide mononitrate) Extended Release and Isordil (isosorbide dinitrate) are vasodilators indicated for the prevention of angina pectoris due to coronary artery disease.. Side effects of Imdur and Isordil that are similar include headache and dizziness.. Side effects of Isordil that are different from Imdur include weakness and skin changes such as redness, tingling, or warmth. Even if the medication is working, you may experience some unwanted side effects. Never take more than the prescribed dose. Enter your medication into the WebMD interaction checker, Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Fitness vs. DUMQOL (DUtch Mononitrate Quality of Life) Study Group. Mayo Clinic on Incontinence - Mayo Clinic Press, NEW The Essential Diabetes Book - Mayo Clinic Press, NEW Ending the Opioid Crisis - Mayo Clinic Press, FREE Mayo Clinic Diet Assessment - Mayo Clinic Press, Mayo Clinic Health Letter - FREE book - Mayo Clinic Press. Symptoms of overdose may include: slow heartbeat, vision changes, severe nausea/vomiting, sweating, cold/clammy skin, bluish fingers/toes/lips. Mayo Clinic does not endorse companies or products. Do not store in the bathroom. Some people feel dizzy or fall when changing positions, such as going from sitting to standing. See the full pregnancy warnings document. The information eHealthMe analyzes includes: Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. Isosorbide mononitrate is used to prevent angina (chest pain) caused by coronary artery disease (heart disease). Nitroglycerin works very quickly to widen your blood vessels and help your heart pump blood during a heart attack. Try to keep your regular appointments with your doctor. Although unlikely, when this medication is used for a long time, it may not work as well and may require different dosing. Isosorbide tablets are also used with other medications to treat heart failure. During pregnancy, this medication should be used only when clearly needed. Watch for any symptoms that you may be having a drug interaction, such as: Mayo Clinic does not endorse companies or products. Herbal supplements and heart medicines may not mix, Your blood pressure, if you also take a drug to treat high blood pressure, Beta blockers, such as atenolol (Tenormin), nadolol (Corgard) or propranolol (Inderal LA, Innopran XL), Calcium channel blockers, such as diltiazem, nifedipine (Procardia) and verapamil (Calan SR, Verelan), Nitrates, such as nitroglycerin (Nitrostat, Nitro-Dur, others) and isosorbide (Isordil, Bidil), Statins, such as atorvastatin (Lipitor), lovastatin (Altoprev) and rosuvastatin (Crestor), Anti-rejection medicine, also called immunosuppressant medicine, such as cyclosporine (Gengraf, Neoral, Sandimmune). US residents can call their local poison control center at 1-800-222-1222. Isosorbide mononitrate Alternatives Compared Isosorbide mononitrate Aspirin Nitroglycerin Prescription only Prescribed for Angina, Heart Failure, Angina Pectoris Prophylaxis. With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. It might help to take isosorbide mononitrate and dinitrate after meals. Consult your doctor before breast-feeding. Isosorbide mononitrate Alternatives Compared Isosorbide mononitrate Aspirin Nitroglycerin Prescription only Prescribed for Angina, Heart Failure, Angina Pectoris Prophylaxis. You may report side effects to the FDA at 1-800-FDA-1088. Store it at room temperature and away from excess heat and moisture (not in the bathroom). There are a number of medications that your doctor can prescribe in place of isosorbide mononitrate (Monoket). Available for Android and iOS devices. It also may keep some medicines from working as well as they should, such as: If your health care provider tells you it's OK to use an herbal supplement along with medicine, be careful. If we combine this information with your protected These side effects may go away during treatment as your body adjusts to the medicine. tell your doctor if you are taking or have recently taken riociguat (Adempas) or a phosphodiesterase inhibitor (PDE-5) such as avanafil (Stendra), sildenafil (Revatio, Viagra), tadalafil (Adcirca, Cialis), and vardenafil (Levitra, Staxyn). All rights reserved. What should I know regarding pregnancy, nursing and administering Isosorbide Mononitrate to children or the elderly? This site complies with the HONcode standard for trustworthy health information: verify here. Ask your pharmacist any questions you have about refilling your prescription. This is called a medicine interaction. 5.0 out of 10 from a total of Mayo Clinic on Incontinence - Mayo Clinic Press, NEW The Essential Diabetes Book - Mayo Clinic Press, NEW Ending the Opioid Crisis - Mayo Clinic Press, FREE Mayo Clinic Diet Assessment - Mayo Clinic Press, Mayo Clinic Health Letter - FREE book - Mayo Clinic Press. Truven Health does not assume any responsibility or risk for your use of the Truven Health products. Store at room temperature away from light and moisture. MBBS, MS - General Surgery, mch neuro surgery. Do infrared saunas have any health benefits? This content does not have an Arabic version. You can take your doses either before or after meals. 72% of reviewers reported a positive effect, while 12% reported a negative effect. Epub 2006 Mar 22. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. sharing sensitive information, make sure youre on a federal Melanoma is one of the most dangerous forms of skin cancer which develops in the skin cells that produce melanin ( the pigment that gives your skin its color). If it is within 2 hours of the next dose, skip the missed dose. These headaches may be a sign that the medication is working as it should. Some of the common derivatives include isosorbide dinitrate and isosorbide mononitrate, which are . . These side effects may go away during treatment as your body adjusts to the medicine. Should I avoid certain foods while taking Isosorbide Mononitrate? Bethesda, MD 20894, Web Policies Cleophas TJ, Niemeyer MG, Zwinderman AH, van der Wall EE. Synthroid (levothyroxine) Tylenol (acetaminophen) Vitamin B12 (cyanocobalamin) Vitamin C (ascorbic acid) Vitamin D3 (cholecalciferol) Isosorbide mononitrate disease interactions There are 7 disease interactions with isosorbide mononitrate which include: AMI anemia hemodialysis hypotension intracranial pressure hypertrophic cardiomyopathy glaucoma Commonly reported side effects include: See also: isosorbide mononitrate side effects in more detail. If you have an underactive thyroid gland. In the remainder of them there was a highly significant time effect: the overall numbers of headache attacks in the first period of active treatment versus the second were 2,380 vs 1,400 (P < 0.003). Additionally, TRUVEN HEALTH MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. Continue to take isosorbide even if you feel well.